England winger Immanuel Fay-Waboso will miss this week's three-day training camp in York as he undergoes a medical examination at Exeter University.
Fay-Waboso, 21, scored a try against Scotland in one of his bright moments during the downturn. Lost in Calcutta Cup.
Halfbacks Alex Mitchell and Marcus Smith have joined the squad to speed up their recovery from injury.
Flanker Tom Pearson is also included in the 36-man group.
The 24-year-old impressed with his try and all-round performance. 'A' Team vs Portugal last Sunday.
England face Grand Slam-chasing Ireland once a week at Twickenham on March 9, but will need a significantly improved performance against a side who have lost just one of their past 21 games.
“We're going to do everything we can to develop,” Borthwick told BBC Radio 5 Live after the defeat at Murrayfield.
“I want to use all the time I have to move forward.”
Borthwick has a lot to think about after suffering a fourth straight defeat to Scotland, with England needing to win their remaining two games to have any chance of competing for the Six Nations title.
Smith's return will provide new playmaking options, while Mitchell is also believed to be recovering faster than expected from his knee injury, although both have resumed full training at this stage. Not ready.
Fay-Waboso is aiming to make his first international start after scoring a try against Scotland, but will miss training this week as he is required to undergo an in-person medical examination.