The top two teams from the two Super 6 groups will advance to the semi-finals of the marquee event.
Pakistan (1.06) are close behind with six points, while India (3.32) occupy the top spot due to their improved net run rate.
Coach Uday Saharan's favorites to win the tournament are yet to taste defeat in the tournament, but Nepal is unlikely to be able to improve on this strong team.
India's superiority is clear from the statistics. Although they are at the top of Group 1 with a perfect record and six points, Nepal are yet to win.
Mushir Khan, the younger brother of Mumbai's prolific batsman Sarfaraz, tops the batting order with 325 runs, an average of over 200 and 81, and his latest breakthrough came against New Zealand on January 30.
Mushir's 131 off 126 balls ushered in India's huge 214-run victory over the Kiwis in the first Super Six match.
Saumi Kumar Pandey then wreaked havoc on New Zealand's batting line-up with four wickets.
The left-arm spinner (12 wickets) currently shares the top spot at the bowling table with Pakistan's Ubaid Shah and South Africa's Kwena Mapaka.
However, India has depth in the team beyond these two obvious stars.
Captain Saharan, wicketkeeper-batsman Aravalli Abanish and explosive all-rounder Arshin Kulkarni also made their presence felt at various stages of the event.
The young stars will be eager to finish their Super Six match on a high and head to Benoni for the last four with confidence.
Opener Adarsh Singh may have had a bit of a hard time getting consistent runs, but his second fifty and 52 here against New Zealand may have given him a sudden burst of confidence.
Left-arm pacer Naman Tiwari, who has effectively controlled the run flow in the powerplay section, could prove a thorn in Nepal's top batsmen.
However, the team from the foothills of the Himalayas has the strength to surprise the strong teams on the day, so it would be naive to ignore Nepal, who had a thrilling victory over Afghanistan in the qualifying stage.
Skipper Dev Karnal (58) and medium pacer Akash Chand (5/34) were the key players in that victory and they will be hoping to make an impression once again. India, on the other hand, will try to avoid mishaps and take a safe path to the semi-finals.
Team (from):
India U19: Uday Saharan (c), Arshin Kulkarni, Adarsh Singh, Rudra Mayur Patel, Sachin Das, Priyanshu Moriya, Mushir Khan, Alavery Avanish Rao, Saumi Kumar Pandey, Murugan -Abhishek, Inesh Mahajan, Dhanush Gowda, Aaradhya Shukla, Raj Limbani and Naman Tiwari.
Nepal U19: Dev Karnal (c), Arjun Kumar, Aakash Tripathi, Dipak Prasad Dumre, Durgesh Gupta, Gulshan Kumar Jha, Dipesh Prasad Khandel, Vishal Bikram KC, Subhash Bhandari, Deepak Bohara, Deepak Bohara, Uttam Rang Thapa Makar, Bipin Rawal, Tilak Raj Bhandari, Akash Chand.
The match begins at 1:30 PM IST.