| venue: twickenham, london date: Saturday, February 10th kick off: 16:45 GMT |
| coverage: Watch live on S4C. Listen on BBC Radio 5 Sports Extra, BBC Radio Wales and Radio Cymru. Text commentary is available on his website and app on BBC Sport. |
Wales flanker James Botham was withdrawn from the Six Nations squad due to a knee injury, with prop Dillon Lewis and lock Seb Davies called up.
Botham started and scored a try in the 27-26 defeat to Scotland, but was sent back to his club Cardiff for rehabilitation.
Lewis becomes Wales' fourth tighthead option in the squad.
Wales face England at Twickenham on Saturday.
Davies can play at lock or in the back row, while Cardiff flanker Alex Mann scored a try on his international debut, replacing Botham against Scotland.
Mackenzie Martin and Tein Basham are the other options in the back row, with Taulupe Faletau and Jack Morgan sidelined through long-term injuries.
Prop Brown started against Scotland, but was sent off at half-time due to injury and was replaced by Keiron Assilatti. Bath's uncapped prop Archie Griffin is another option for the team.
Lewis, 28, has made 54 appearances for Wales. The former Cardiff man is one of three tighthead props selected for the 2023 World Cup, along with France-based Henry Thomas and Thomas Francis, who were not included in the original Six Nations squad. was.
Fly-half Sam Costelow is doubtful to feature against England after being taken off the field in the first half with a head injury after being taken out of a ruck.
He was replaced by Yoan Lloyd, who is set to make his first fly-half start for Wales at Twickenham.
